The smart Trick of ceesdekker That Nobody is Discussing
Midway via his job, Cees Dekker reinvented himself. Right after many years of hardcore physics, he shifted his concentration to ‘nanobiology’ on the transform in the millennium. A time period he coined himself, like a make any difference of truth.It absolutely was only inside the nineteen nineties although, when nanotechnology experienced Sophisticated to your level wherever single molecules may be manipulated, that the first experimental units commenced to appear.
, Groningen scientists existing the results of their efforts to create labs a lot more sustainable and provide methods for other labs.Â
2007, 1st serious-time detection of strand exchange in homologous recombination by RecA; discovery of a very low persistence length of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and very first at any time examine of the dynamics DNA supercoils and the invention of supercoil hopping
Experimental stage diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
MATLAB codes for information processing are offered at . Julia codes employed for numerical simulation are available at .
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Knowledge essential ceesdekker procedures regulating the spatial and dynamic organisation of the DNA in live cells.
At this time, we also realized that it ought to be doable to implement one semiconducting carbon nanotube to generate a transistor — and we established out to make it. We stretched person semiconducting nanotubes throughout metallic electrodes and applied the fundamental silicon substrate like a gate electrode, setting up the basic a few-terminal format of a field-outcome transistor (Fig.
Case in point (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in gray, the rim on the pore is highlighted in crimson, along with a 3D rendering of your movement in the DNA rod is displayed.
Afterwards we spoke once again briefly for the reason that Dekker felt that our discussion of his faith swiftly grew to become purely philosophical, While In addition it concretely helps him in his function.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
 Finally, I will briefly sketch some of our Suggestions to investigate the constructing of artificial cells, exclusively our initially ways to determine artificial mobile division.